Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GPR183 | P32249 | 8/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735480 | 1.00 | MAPT (0.59) | MAPTHPGDALDH1A1NPC1RAB9A | |
| SCHEMBL9735594 | 0.88 | MEN1 (0.57) | MAPTHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9735590 | 0.88 | MEN1 (0.57) | MAPTHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9735192 | 0.88 | GPR183 (0.58) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9735198 | 0.88 | GPR183 (0.58) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9735965 | 0.79 | PKM (0.51) | HPGDALDH1A1LMNA | |
| SCHEMBL7950882 | 0.76 | NAMPT (0.51) | ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL7950888 | 0.76 | NAMPT (0.51) | ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL8824257 | 0.76 | L3MBTL1 (0.62) | MAPTALDH1A1SMN1; SMN2GPR183LMNA | |
| SCHEMBL11479548 | 0.74 | MAPT (0.74) | MAPTHPGDALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102882-A | Nootropic agents | NIPPON SHINYAKU CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |