Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | FASN | P49327 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735854 | 0.86 | KMT2A (0.58) | HPGDALDH1A1POLBMEN1KMT2A | |
| SCHEMBL9735965 | 0.86 | PKM (0.51) | NAMPTHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL9736472 | 0.86 | HSD11B1 (0.51) | NAMPTKDM4EALDH1A1POLBL3MBTL1 | |
| SCHEMBL9735561 | 0.86 | POLB (0.57) | HPGDALDH1A1POLBL3MBTL1MEN1 | |
| SCHEMBL9734377 | 0.85 | HPGD (0.54) | HPGDKDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL7950888 | 0.83 | NAMPT (0.51) | NAMPTTGM2ALDH1A1POLBL3MBTL1 | |
| SCHEMBL7950882 | 0.83 | NAMPT (0.51) | NAMPTTGM2ALDH1A1POLBL3MBTL1 | |
| SCHEMBL9735387 | 0.83 | NAMPT (0.67) | NAMPTSIGMAR1TGM2ALDH1A1USP2 | |
| SCHEMBL9734991 | 0.83 | HPGD (0.55) | HPGDALDH1A1POLBL3MBTL1MEN1 | |
| SCHEMBL9735575 | 0.83 | RAB9A (0.56) | NAMPTHPGDKDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102882-A | Nootropic agents | NIPPON SHINYAKU CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |