Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1626517 | 0.81 | DRD2 (0.44) | KMT2ATSHRMAPK1CYP2D6LMNA | |
| SCHEMBL1625990 | 0.77 | HTT (0.43) | TSHRCYP2C19CYP1A2CYP2D6LMNA | |
| SCHEMBL28369144 | 0.75 | KMT2A (0.56) | KMT2AMEN1L3MBTL1TSHRMAPK1 | |
| SCHEMBL693455 | 0.72 | KMT2A (1.00) | KMT2AMEN1L3MBTL1TSHRMAPK1 | |
| SCHEMBL29843194 | 0.70 | KMT2A (0.66) | KMT2AMEN1L3MBTL1TSHRMAPK1 | |
| SCHEMBL1033548 | 0.70 | KMT2A (0.66) | KMT2AMEN1L3MBTL1TSHRMAPK1 | |
| SCHEMBL3007964 | 0.70 | KMT2A (0.66) | KMT2AMEN1L3MBTL1TSHRMAPK1 | |
| SCHEMBL1626519 | 0.70 | ALDH1A1 (0.34) | KMT2AMEN1TSHRMAPK1LMNA | |
| SCHEMBL9735045 | 0.69 | KMT2A (0.49) | KMT2AMEN1L3MBTL1TSHRMAPK1 | |
| SCHEMBL2815639 | 0.69 | KMT2A (0.64) | KMT2AMEN1L3MBTL1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173503-A | Derivatives of N,N-dimethyl-4-phenylalkylenesulfonyl-imidazole -1-sulphonamides; phytopathogenic fungi | SCHERING AGROCHEMICALS LIMITED (GB) | 1992-12-22 | — | — | US | disclosed |
| EP-0432892-A1 | Imidazole fungicides | AgrEvo UK Limited (GB) | 1991-06-19 | — | — | EP | disclosed |