Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736504 | 0.86 | OPRM1 (0.40) | MEN1KMT2APRMT5ADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL10829874 | 0.85 | ABCB1 (0.52) | LMNACYP1A2CYP2D6SCN1ASCN2A | |
| SCHEMBL10830708 | 0.85 | ABCB1 (0.51) | LMNACYP1A2CYP2D6SCN1ASCN2A | |
| SCHEMBL10830619 | 0.83 | ABCB1 (0.48) | LMNACYP1A2CYP2D6SCN1ASCN2A | |
| SCHEMBL9735739 | 0.81 | OPRM1 (0.37) | MEN1KMT2AALDH1A1 | |
| SCHEMBL9737525 | 0.81 | KDM4E (0.38) | MEN1KMT2APOLBPRMT5KDM4E | |
| Hydrochloric Acid SCHEMBL10829780 | 0.80 | MEN1 (0.45) | LMNACYP1A2CYP2D6SCN1ASCN2A | |
| SCHEMBL9742031 | 0.79 | OPRM1 (0.41) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9736627 | 0.77 | MEN1 (0.43) | LMNACYP2D6ABCB1MEN1KMT2A | |
| SCHEMBL10991865 | 0.76 | KMT2A (0.42) | LMNACYP1A2CYP2D6SCN1ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118685-A | Antiarrhythmia agents | BASF AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |