Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | HAT1 | O14929 | 2/20 | 0.37 |
| ▸ | EP300 | Q09472 | 2/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | CTSV | O60911 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735739 | 0.87 | OPRM1 (0.37) | OPRM1HAT1EP300JAK2JAK1 | |
| SCHEMBL9737525 | 0.86 | KDM4E (0.38) | OPRM1HAT1EP300ADRB1ADRB2 | |
| SCHEMBL9735615 | 0.86 | LMNA (0.44) | ADRB1ADRB2ADRB3PRMT5MEN1 | |
| SCHEMBL9742031 | 0.84 | OPRM1 (0.41) | OPRM1HAT1EP300ADRB1ADRB2 | |
| Hydrochloric Acid SCHEMBL10829694 | 0.83 | ADRB1 (0.45) | ADRB1ADRB2ADRB3CA12CA1 | |
| SCHEMBL9736627 | 0.83 | MEN1 (0.43) | L3MBTL1MEN1KMT2A | |
| SCHEMBL9737262 | 0.81 | ABCB1 (0.49) | ADRB1ADRB2ADRB3KMT2A | |
| SCHEMBL9736392 | 0.81 | ADRB2 (0.60) | ADRB1ADRB2ADRB3MEN1KMT2A | |
| SCHEMBL9735892 | 0.78 | ABCB1 (0.51) | MEN1KMT2A | |
| SCHEMBL9735929 | 0.76 | OPRM1 (0.44) | OPRM1HAT1EP300JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118685-A | Antiarrhythmia agents | BASF AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |