Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.37 |
| ▸ | HAT1 | O14929 | 2/20 | 0.36 |
| ▸ | EP300 | Q09472 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | CTSV | O60911 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736504 | 0.87 | OPRM1 (0.40) | OPRM1HAT1EP300OPRK1MEN1 | |
| SCHEMBL9736627 | 0.87 | MEN1 (0.43) | MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL9737262 | 0.83 | ABCB1 (0.49) | KMT2AALDH1A1PKM | |
| SCHEMBL9737525 | 0.82 | KDM4E (0.38) | OPRM1HAT1EP300MEN1KMT2A | |
| SCHEMBL9735615 | 0.81 | LMNA (0.44) | MEN1KMT2AALDH1A1 | |
| SCHEMBL9742031 | 0.80 | OPRM1 (0.41) | OPRM1HAT1EP300OPRK1MEN1 | |
| SCHEMBL9735892 | 0.80 | ABCB1 (0.51) | MEN1KMT2A | |
| Oxalic Acid SCHEMBL10829714 | 0.80 | MDM2 (0.46) | KCNH2PKMMDM2 | |
| SCHEMBL9735929 | 0.77 | OPRM1 (0.44) | OPRM1HAT1EP300OPRK1JAK2 | |
| SCHEMBL9736392 | 0.77 | ADRB2 (0.60) | MEN1KMT2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118685-A | Antiarrhythmia agents | BASF AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |