Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.57 |
| ▸ | BCHE | P06276 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | CASP7 | P55210 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9107151 | 0.76 | ACHE (0.82) | ACHEBCHEALDH1A1KCNH2KDM4E | |
| SCHEMBL8781795 | 0.73 | ACHE (0.62) | ACHEBCHEALDH1A1KCNH2KDM4E | |
| SCHEMBL9106523 | 0.73 | ACHE (1.00) | ACHEBCHEALDH1A1KCNH2KDM4E | |
| SCHEMBL16381051 | 0.73 | NUDT1 (0.41) | ALDH1A1KDM4EHPGDCASP1HSD17B10 | |
| SCHEMBL9108559 | 0.73 | ACHE (0.59) | ACHEBCHEALDH1A1KCNH2KDM4E | |
| Hydrochloric Acid SCHEMBL10656143 | 0.72 | ACHE (0.97) | ACHEBCHEALDH1A1KCNH2KDM4E | |
| SCHEMBL9583492 | 0.70 | ACHE (0.59) | ACHEBCHEALDH1A1KCNH2KDM4E | |
| SCHEMBL4782557 | 0.68 | ACHE (0.53) | ACHEBCHEALDH1A1KCNH2KDM4E | |
| SCHEMBL9172816 | 0.68 | ACHE (0.63) | ACHEBCHEALDH1A1KCNH2KDM4E | |
| SCHEMBL9171459 | 0.68 | ACHE (0.63) | ACHEBCHEALDH1A1KCNH2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112830-A | Cognition Activators | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1992-05-12 | — | — | US | claimed |