Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DBH | P09172 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | TTR | P02766 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735145 | 0.88 | MAPK1 (0.49) | DBHMAPK1VCAM1CRHBPCRHR2 | |
| SCHEMBL1658633 | 0.79 | LMNA (0.48) | DBHMAPK1VCAM1MAPTTTR | |
| SCHEMBL7047895 | 0.78 | TTR (0.73) | DBHMAPK1VCAM1CRHBPCRHR2 | |
| SCHEMBL31448608 | 0.78 | MAPK1 (0.51) | DBHMAPK1VCAM1CRHBPCRHR2 | |
| SCHEMBL7618780 | 0.78 | VCAM1 (0.51) | DBHMAPK1VCAM1MAPTTTR | |
| SCHEMBL12082320 | 0.78 | CDK2 (0.52) | DBHMAPK1VCAM1MAPTTTR | |
| SCHEMBL31448571 | 0.76 | MAPK1 (0.53) | DBHMAPK1VCAM1CRHBPCRHR2 | |
| SCHEMBL31448639 | 0.76 | MAPK1 (0.53) | DBHMAPK1VCAM1CRHBPCRHR2 | |
| SCHEMBL27815588 | 0.76 | ALDH1A1 (0.62) | DBHMAPK1VCAM1MAPTTTR | |
| SCHEMBL2837833 | 0.75 | ALDH1A1 (0.52) | MAPK1VCAM1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086128-A | HIGH MOLECULAR WEIGHT ARYLENE SULPHIDE POLYMER MELT MIXED WITH AROMATIC NITRO COMPOUND | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-04 | — | — | US | disclosed |