Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | F7 | P08709 | 4/20 | 0.49 |
| ▸ | F3 | P13726 | 4/20 | 0.49 |
| ▸ | PPARG | P37231 | 4/20 | 0.49 |
| ▸ | PPARD | Q03181 | 4/20 | 0.49 |
| ▸ | PPARA | Q07869 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | FABP4 | P15090 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.49 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.49 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.49 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10428746 | 1.00 | ALDH1A1 (0.49) | ALDH1A1F7F3PPARGPPARD | |
| SCHEMBL11593812 | 0.97 | ALDH1A1 (0.54) | ALDH1A1F7F3PPARGPPARD | |
| SCHEMBL13949151 | 0.96 | PPARG (0.53) | ALDH1A1F7F3PPARGPPARD | |
| SCHEMBL5580017 | 0.91 | TBXAS1 (0.47) | ALDH1A1PPARGPPARDPPARAFABP4 | |
| SCHEMBL5580070 | 0.91 | TBXAS1 (0.47) | ALDH1A1PPARGPPARDPPARAFABP4 | |
| SCHEMBL3199941 | 0.91 | TBXAS1 (0.47) | ALDH1A1PPARGPPARDPPARAFABP4 | |
| SCHEMBL2944337 | 0.91 | TBXAS1 (0.47) | ALDH1A1PPARGPPARDPPARAFABP4 | |
| SCHEMBL5966061 | 0.89 | TBXAS1 (0.44) | TDP1FAAHKMT2ATBXA2RMEN1 | |
| SCHEMBL13092461 | 0.89 | ALDH1A1 (0.42) | ALDH1A1F7F3PPARGPPARD | |
| SCHEMBL13092462 | 0.89 | ALDH1A1 (0.42) | ALDH1A1F7F3PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126125-A | Decreasing the melanin content in mammalian skin and hair using 5,6-dihydroxindole derivatives | YALE UNIVERSITY (US) | 1992-06-30 | — | — | US | disclosed |
| US-4956174-A | COSMETICS, TANNING, PIGMENTATION | L'OREAL (FR) | 1990-09-11 | — | — | US | disclosed |
| US-4822375-A | LIGHTFAST, WEATHER RESISTANT, NATURAL APPEARING HAIR DYES | L'OREAL (FR) | 1989-04-18 | — | — | US | disclosed |
| EP-0239826-A1 | Skin-tanning compositions containing indole derivatives | L'OREAL (FR) | 1987-10-07 | — | — | EP | disclosed |