SCHEMBL2944337

SCHEMBL2944337

CCCCCCCCCCCCCCCCCC(=O)n1ccnc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 6/20 0.47
TBXA2R P21731 2/20 0.44
CES2 O00748 3/20 0.41
CES1 P23141 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
FAAH O00519 1/20 0.41
NAAA Q02083 1/20 0.41
TDP1 Q9NUW8 3/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
PPARG P37231 3/20 0.39
PPARD Q03181 3/20 0.39
PPARA Q07869 3/20 0.39
TSHR P16473 2/20 0.39
GPR84 Q9NQS5 2/20 0.39
HDAC11 Q96DB2 2/20 0.39
ALDH1A1 P00352 1/20 0.39
SLC22A6 Q4U2R8 1/20 0.39
SLC22A8 Q8TCC7 1/20 0.39
TLR2 O60603 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5580070 1.00 TBXAS1 (0.47) TBXAS1TBXA2RCES2CES1L3MBTL1
SCHEMBL5579728 1.00 TBXAS1 (0.47) TBXAS1TBXA2RCES2CES1L3MBTL1
SCHEMBL5966050 1.00 TBXAS1 (0.47) TBXAS1TBXA2RCES2CES1L3MBTL1
SCHEMBL5580017 1.00 TBXAS1 (0.47) TBXAS1TBXA2RCES2CES1L3MBTL1
SCHEMBL3199941 1.00 TBXAS1 (0.47) TBXAS1TBXA2RCES2CES1L3MBTL1
SCHEMBL20078981 1.00 TBXAS1 (0.47) TBXAS1TBXA2RCES2CES1L3MBTL1
SCHEMBL5966061 0.98 TBXAS1 (0.44) TBXAS1TBXA2RCES2CES1L3MBTL1
SCHEMBL28774336 0.93 TBXAS1 (0.42) TBXAS1TBXA2RCES2CES1TDP1
SCHEMBL9735799 0.91 ALDH1A1 (0.49) TBXA2RFAAHTDP1MEN1KMT2A
SCHEMBL10428746 0.91 ALDH1A1 (0.49) TBXA2RFAAHTDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100273116-A1 SILVER HALIDE PHOTOSENSITIVE MATERIAL FUJIFILM CORPORATION (JP) 2010-10-28 US disclosed
EP-1797124-B1 COVALENT GRAFTING OF HYDROPHOBIC SUBSTANCES ON COLLAGEN BIOM UP (FR) 2010-09-01 EP disclosed
US-20070260299-A1 Covalent Grafting of Hydrophobic Substances on Collagen INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON (FR) 2007-11-08 US disclosed
EP-1797124-A1 COVALENT GRAFTING OF HYDROPHOBIC SUBSTANCES ON COLLAGEN INSA (Institut National des Sciences Appliqées) (FR) 2007-06-20 EP disclosed
WO-2006037770-A1 COVALENT GRAFTING OF HYDROPHOBIC SUBSTANCES ON COLLAGEN INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON (FR) 2006-04-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070260299-A1 Covalent Grafting of Hydrophobic Substances on Collagen COL14A1, COL1A1, COL2A1 TBXAS1 2651/4885TBXA2R 2777/4885CES2 559/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.