Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 2/20 | 0.35 |
| ▸ | MMP13 | P45452 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | HMGCR | P04035 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29064066 | 0.93 | MMP12 (0.37) | MMP12MMP13MMP2MMP9MMP14 | |
| SCHEMBL9735944 | 0.93 | MMP12 (0.37) | MMP12MMP13MMP2MMP9MMP14 | |
| SCHEMBL3898515 | 0.87 | PTPRC (0.36) | ADRB2ADRB1ADRB3 | |
| SCHEMBL24312400 | 0.84 | CYP2D6 (0.38) | ADRB2ADRB1ADRB3CYP3A4HTT | |
| SCHEMBL9736771 | 0.83 | ADRB2 (0.36) | ADRB2ADRB1ADRB3CYP3A4HTT | |
| SCHEMBL7155286 | 0.82 | CYP2D6 (0.37) | ADRB2ADRB1ADRB3CYP3A4HTT | |
| SCHEMBL9523633 | 0.82 | GAA (0.36) | ADRB2ADRB1ADRB3CYP3A4HTT | |
| SCHEMBL8122701 | 0.82 | GAA (0.36) | ADRB2ADRB1ADRB3CYP3A4HTT | |
| SCHEMBL8122702 | 0.82 | GAA (0.36) | ADRB2ADRB1ADRB3CYP3A4HTT | |
| SCHEMBL14481513 | 0.82 | FFAR1 (0.38) | CYP3A4HTTSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2752407-B1 | Crystalline rosuvastatin calcium trihydrate | KRKA TOVARNA ZDRAVIL D D NOVO MESTO (SI) | 2015-09-23 | — | — | EP | disclosed |
| EP-2752407-A1 | Crystalline rosuvastatin calcium trihydrate | Krka Tovarna Zdravil, D.D., Novo Mesto (SI) | 2014-07-09 | — | — | EP | disclosed |
| EP-2387566-B1 | PROCESS FOR THE PREPARATION OF ROSUVASTATIN | KRKA TOVARNA ZDRAVIL D D NOVO MESTO (SI) | 2014-05-07 | — | — | EP | disclosed |
| US-5093363-A | Antilipemic agents | SHIONOGI & CO., LTD. (JP) | 1992-03-03 | — | — | US | disclosed |
| EP-0414206-A2 | 2,4,6-Substituted phenol derivatives | SHIONOGI & CO., LTD. (JP) | 1991-02-27 | — | — | EP | disclosed |