Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 9/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 9/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | BRS3 | P32247 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6007921 | 0.90 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL9737230 | 0.84 | FOLH1 (0.44) | FOLH1AGTR1AGTR2 | |
| SCHEMBL9530302 | 0.82 | AGTR1 (0.47) | FOLH1AGTR1AGTR2 | |
| SCHEMBL6004604 | 0.82 | AGTR1 (0.61) | AGTR1AGTR2 | |
| SCHEMBL6006020 | 0.81 | AGTR1 (0.61) | AGTR1AGTR2 | |
| SCHEMBL9529085 | 0.81 | FOLH1 (0.45) | FOLH1AGTR1AGTR2 | |
| SCHEMBL6004755 | 0.81 | AGTR1 (0.60) | AGTR1AGTR2BRS3 | |
| SCHEMBL6007223 | 0.79 | AGTR1 (0.44) | AGTR1AGTR2BRS3 | |
| SCHEMBL6004801 | 0.79 | AGTR1 (0.50) | AGTR1AGTR2BRS3 | |
| SCHEMBL6007106 | 0.79 | AGTR1 (0.46) | AGTR1AGTR2BRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992004335-A2 | RENAL-SELECTIVE BIPHENYLALKYL 1H-SUBSTITUTED-1,2,4-TRIAZOLE ANGIOTENSIN II ANTAGONISTS FOR TREATMENT OF HYPERTENSION | G.D. SEARLE & CO. (US) | 1992-03-19 | — | — | WO | disclosed |