Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 10/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 10/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530302 | 0.94 | AGTR1 (0.47) | FOLH1AGTR1AGTR2 | |
| SCHEMBL6007873 | 0.89 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL9529085 | 0.87 | FOLH1 (0.45) | FOLH1AGTR1AGTR2 | |
| SCHEMBL9553474 | 0.86 | FOLH1 (0.44) | FOLH1AGTR1AGTR2 | |
| SCHEMBL9735863 | 0.84 | FOLH1 (0.39) | FOLH1AGTR1AGTR2 | |
| SCHEMBL9528852 | 0.84 | FOLH1 (0.41) | FOLH1AGTR1AGTR2 | |
| SCHEMBL9528847 | 0.84 | FOLH1 (0.41) | FOLH1AGTR1AGTR2 | |
| SCHEMBL6005831 | 0.83 | AGTR1 (0.59) | AGTR1AGTR2 | |
| SCHEMBL9738591 | 0.82 | AGTR1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL9552165 | 0.82 | AGTR1 (0.43) | FOLH1AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992004335-A2 | RENAL-SELECTIVE BIPHENYLALKYL 1H-SUBSTITUTED-1,2,4-TRIAZOLE ANGIOTENSIN II ANTAGONISTS FOR TREATMENT OF HYPERTENSION | G.D. SEARLE & CO. (US) | 1992-03-19 | — | — | WO | disclosed |