Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11102739 | 0.90 | CYP1A2 (0.56) | ALDH1A1SMN1; SMN2KDM4ELMNAHPGD | |
| SCHEMBL14880629 | 0.78 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL16497591 | 0.77 | KDM1A (0.40) | LMNAHTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL14880347 | 0.72 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL1224368 | 0.71 | CFTR (0.48) | ALDH1A1KMT2AMAPTLMNACYP1A2 | |
| SCHEMBL18533598 | 0.67 | HTR3A (0.52) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL3952742 | 0.64 | CYP1A2 (0.73) | ALDH1A1LMNAPOLBHPGDCYP1A2 | |
| SCHEMBL11165087 | 0.64 | CYP1A2 (0.73) | ALDH1A1LMNAPOLBHPGDCYP1A2 | |
| SCHEMBL28215 | 0.64 | CYP1A2 (0.73) | ALDH1A1LMNAPOLBHPGDCYP1A2 | |
| SCHEMBL10690598 | 0.63 | MEN1 (0.55) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134152-A | 1,2,4-Triazole compounds | SANKYO COMPANY, LIMITED (JP) | 1992-07-28 | — | — | US | disclosed |