Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736130 | 0.87 | NAMPT (0.61) | NAMPTSMN1; SMN2AKR1C3MEN1KMT2A | |
| SCHEMBL9735387 | 0.86 | NAMPT (0.67) | NAMPTSMN1; SMN2USP2MAPK1MAPT | |
| SCHEMBL9736530 | 0.85 | MAPT (0.61) | NAMPTSMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL9736472 | 0.84 | HSD11B1 (0.51) | NAMPTCA12CA1CA2CA9 | |
| SCHEMBL9734450 | 0.84 | NAMPT (0.58) | NAMPTSMN1; SMN2MAPK1CA12CA1 | |
| SCHEMBL7950888 | 0.81 | NAMPT (0.51) | NAMPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL7950882 | 0.81 | NAMPT (0.51) | NAMPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL9735095 | 0.81 | PARP1 (0.51) | — | |
| SCHEMBL9736057 | 0.77 | POLB (0.65) | NAMPTSMN1; SMN2USP2MAPK1MEN1 | |
| SCHEMBL7955572 | 0.77 | NAMPT (0.48) | NAMPTSMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102882-A | Nootropic agents | NIPPON SHINYAKU CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |