Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735951 | 0.87 | NAMPT (0.61) | NAMPTMEN1KMT2AAKR1C3ALDH1A1 | |
| SCHEMBL9735387 | 0.86 | NAMPT (0.67) | NAMPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL9736530 | 0.85 | MAPT (0.61) | NAMPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL9735854 | 0.84 | KMT2A (0.58) | MEN1KMT2AAKR1C3ALDH1A1HPGD | |
| SCHEMBL9734450 | 0.84 | NAMPT (0.58) | NAMPTGFERAKR1C3LMNAALDH1A1 | |
| SCHEMBL9735532 | 0.82 | PARP1 (0.49) | KMT2AAKR1C3ALDH1A1HTTNPSR1 | |
| SCHEMBL7950882 | 0.81 | NAMPT (0.51) | NAMPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7950888 | 0.81 | NAMPT (0.51) | NAMPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9734613 | 0.81 | GFER (0.50) | NAMPTMEN1KMT2AGFERALDH1A1 | |
| SCHEMBL9737198 | 0.81 | NAMPT (0.54) | NAMPTMEN1KMT2AAKR1C3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102882-A | Nootropic agents | NIPPON SHINYAKU CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |