Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.37 |
| ▸ | CHRNG | P07510 | 1/20 | 0.37 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.37 |
| ▸ | CHRND | Q07001 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 4/20 | 0.35 |
| ▸ | MAOA | P21397 | 4/20 | 0.35 |
| ▸ | MAOB | P27338 | 4/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15007138 | 0.70 | CHRNB2 (0.33) | CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL2598217 | 0.70 | CHRNB2 (0.33) | CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL10795410 | 0.69 | SLC6A2 (0.44) | CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7358282 | 0.68 | GAA (0.38) | KMT2ACA2LMNAADORA3 | |
| SCHEMBL7358289 | 0.68 | GAA (0.38) | KMT2ACA2LMNAADORA3 | |
| SCHEMBL23123719 | 0.67 | SLC6A2 (0.41) | CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL9051041 | 0.66 | SLC6A2 (0.44) | SLC6A2SLC6A3KMT2AUSP2KDM1A | |
| SCHEMBL10473935 | 0.66 | — | — | |
| SCHEMBL10332615 | 0.66 | DDB1 (0.41) | USP2CA2LMNAADORA3KDM1A | |
| SCHEMBL7687072 | 0.64 | ALDH1A1 (0.39) | KMT2AUSP2LMNAADORA3KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089614-A | Polysubstituted 2-morpholones | THE B. F. GOODRICH COMPANY (US) | 1992-02-18 | — | — | US | disclosed |
| US-4914232-A | FOR POLYMERS | THE B. F. GOODRICH COMPANY (US) | 1990-04-03 | — | — | US | disclosed |
| US-4528370-A | Polysubstituted 2-morpholones | NOVEON IP HOLDINGS CORP., FORMERLY KNOWN AS PMD HOLDINGS CORP. | 1985-07-09 | — | — | US | disclosed |