Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.45 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736472 | 0.87 | HSD11B1 (0.51) | ALDH1A1MEN1KMT2AHSD11B1MGLL | |
| SCHEMBL9735854 | 0.87 | KMT2A (0.58) | ALDH1A1MEN1KMT2AHPGDHSD11B1 | |
| SCHEMBL9734952 | 0.86 | NAMPT (0.52) | ALDH1A1MEN1KMT2AHPGDNAMPT | |
| SCHEMBL9734991 | 0.86 | HPGD (0.55) | ALDH1A1MEN1KMT2AHPGDHSD11B1 | |
| SCHEMBL9734377 | 0.85 | HPGD (0.54) | MEN1KMT2AHPGDHSD11B1MGLL | |
| SCHEMBL9735743 | 0.83 | KMT2A (0.61) | ALDH1A1MEN1KMT2AHPGDHSD11B1 | |
| SCHEMBL7950888 | 0.81 | NAMPT (0.51) | ALDH1A1MEN1KMT2ANAMPT | |
| SCHEMBL7950882 | 0.81 | NAMPT (0.51) | ALDH1A1MEN1KMT2ANAMPT | |
| SCHEMBL8824257 | 0.81 | L3MBTL1 (0.62) | ALDH1A1LMNA | |
| SCHEMBL9734955 | 0.81 | HTT (0.57) | ALDH1A1MEN1KMT2AHPGDHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102882-A | Nootropic agents | NIPPON SHINYAKU CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |