Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | KIF11 | P52732 | 7/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735990 | 1.00 | CA1 (0.49) | CA1CA2KIF11EPHX2TGM2 | |
| SCHEMBL9734844 | 0.79 | SMN1; SMN2 (0.49) | CA1CA2TGM2MEN1KMT2A | |
| SCHEMBL9734847 | 0.79 | SMN1; SMN2 (0.49) | CA1CA2TGM2MEN1KMT2A | |
| SCHEMBL9735698 | 0.78 | RAB9A (0.49) | CA1CA2TGM2CA12MEN1 | |
| SCHEMBL9735087 | 0.78 | CA1 (0.48) | CA1CA2KIF11CA12MEN1 | |
| SCHEMBL9735705 | 0.78 | RAB9A (0.49) | CA1CA2TGM2CA12MEN1 | |
| SCHEMBL9735736 | 0.78 | MAPT (0.51) | CA1CA2MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL9736370 | 0.78 | SMN1; SMN2 (0.48) | CA1CA2TGM2MEN1KMT2A | |
| SCHEMBL9735732 | 0.78 | MAPT (0.51) | CA1CA2MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL9736367 | 0.78 | SMN1; SMN2 (0.48) | CA1CA2TGM2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112866-A | Sulfonylfluorides as intermediates, also useful in treatment of bone disorders, antisecretory, antiulcer | ORTHO PHARMACEUTICAL CORPORATION (US) | 1992-05-12 | — | — | US | disclosed |