Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
| ▸ | GABRE | P78334 | 1/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7953519 | 0.90 | LMNA (0.42) | POLBDUSP3PTPN5PTPN11ALDH1A1 | |
| SCHEMBL7948011 | 0.82 | TP53 (0.38) | ADORA3GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL7941792 | 0.82 | SMN1; SMN2 (0.43) | POLBADORA3ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7951665 | 0.79 | LMNA (0.40) | ADORA3ADORA1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7949177 | 0.74 | KDM4E (0.51) | ALDH1A1KDM4ESMN1; SMN2RAB9ALMNA | |
| SCHEMBL7949052 | 0.71 | KMT2A (0.44) | POLBALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL7941798 | 0.70 | PGR (0.46) | KDM4ELMNAMAPK1MEN1KMT2A | |
| SCHEMBL7949077 | 0.69 | MAPT (0.42) | POLBALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL7949731 | 0.69 | HSP90AA1 (0.41) | POLBADORA3ADORA1ALDH1A1KDM4E | |
| SCHEMBL7941785 | 0.69 | LMNA (0.39) | POLBADORA3SMN1; SMN2RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130430-A | Anxiety, sleep disorders or seizures | NEUROGEN CORPORATION (US) | 1992-07-14 | — | — | US | claimed |
| US-5130430-A | Anxiety, sleep disorders or seizures | NEUROGEN CORPORATION (US) | 1992-07-14 | — | — | US | disclosed |