Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736123 | 1.00 | GCGR (0.37) | GCGRTP53THRBKDM1AIDO1 | |
| SCHEMBL9383734 | 0.90 | GCGR (0.40) | GCGRTP53THRBKDM1AIDO1 | |
| SCHEMBL9384186 | 0.87 | GCGR (0.38) | GCGRTP53ALDH1A1 | |
| SCHEMBL9735137 | 0.87 | GCGR (0.38) | GCGRTP53ALDH1A1 | |
| SCHEMBL9388048 | 0.86 | KDM4E (0.45) | GCGRCYP1A2CYP2C19KMT2ASMN1; SMN2 | |
| SCHEMBL9736896 | 0.86 | KDM4E (0.45) | GCGRCYP1A2CYP2C19KMT2ASMN1; SMN2 | |
| SCHEMBL9735571 | 0.81 | GCGR (0.39) | GCGRIDO1CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL9383069 | 0.81 | GCGR (0.39) | GCGRIDO1CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL7791791 | 0.79 | GCGR (0.40) | GCGRSMN1; SMN2ALDH1A1 | |
| SCHEMBL9772121 | 0.79 | HMGCR (0.60) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145959-A | Enzyme inhibitors; antilipemic agents; treatment of atherosclerosis | BAYER AKTIENGESELLSCHAFT (DE) | 1992-09-08 | — | — | US | disclosed |
| US-5075311-A | Anticholesterol agents | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-24 | — | — | US | disclosed |