Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9388048 | 1.00 | KDM4E (0.45) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL9384186 | 0.91 | GCGR (0.38) | KDM4EALDH1A1MAPK1RXFP1PDE4A | |
| SCHEMBL9383396 | 0.91 | KDM4E (0.48) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL9735137 | 0.91 | GCGR (0.38) | KDM4EALDH1A1MAPK1RXFP1PDE4A | |
| SCHEMBL9736133 | 0.86 | GCGR (0.37) | ALDH1A1KMT2ACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL9736123 | 0.86 | GCGR (0.37) | ALDH1A1KMT2ACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL9734749 | 0.85 | KDM4E (0.44) | KDM4EALDH1A1HTTMAPK1RXFP1 | |
| SCHEMBL9734676 | 0.82 | HMGCR (0.43) | KDM4EALDH1A1HTTRXFP1CYP3A4 | |
| SCHEMBL9734698 | 0.82 | HMGCR (0.43) | KDM4EALDH1A1HTTRXFP1CYP3A4 | |
| SCHEMBL9387249 | 0.82 | GCGR (0.54) | KDM4EALDH1A1HTTGCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145959-A | Enzyme inhibitors; antilipemic agents; treatment of atherosclerosis | BAYER AKTIENGESELLSCHAFT (DE) | 1992-09-08 | — | — | US | disclosed |
| US-5075311-A | Anticholesterol agents | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-24 | — | — | US | disclosed |