Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | CDC25A | P30304 | 5/20 | 0.38 |
| ▸ | CDC25B | P30305 | 5/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.37 |
| ▸ | F13A1 | P00488 | 3/20 | 0.36 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9669858 | 0.80 | PDCD4 (0.36) | FFAR4FFAR1TRPA1NR4A2PTGER4 | |
| SCHEMBL9669841 | 0.80 | PDCD4 (0.36) | FFAR4FFAR1TRPA1NR4A2PTGER4 | |
| SCHEMBL9838197 | 0.74 | F13A1 (0.46) | F13A1 | |
| SCHEMBL6907995 | 0.64 | TBXAS1 (0.58) | FFAR4FFAR1LTB4R | |
| SCHEMBL9308449 | 0.64 | TBXAS1 (0.58) | FFAR4FFAR1LTB4R | |
| SCHEMBL2181858 | 0.63 | FFAR4 (0.79) | FFAR4FFAR1GSTK1 | |
| SCHEMBL5742369 | 0.63 | FFAR4 (0.79) | FFAR4FFAR1GSTK1 | |
| SCHEMBL15009701 | 0.63 | FFAR4 (0.79) | FFAR4FFAR1GSTK1 | |
| SCHEMBL5672920 | 0.63 | FFAR4 (0.79) | FFAR4FFAR1GSTK1 | |
| SCHEMBL22612709 | 0.63 | FFAR4 (0.79) | FFAR4FFAR1GSTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134128-A | Immunosuppressive and antiproliferative activity for psoriasis and calcium homeostasis | ALLERGAN, INC. (US) | 1992-07-28 | — | — | US | disclosed |
| EP-0295056-A1 | Anti-inflammatory furanones | ALLERGAN, INC (US) | 1988-12-14 | — | — | EP | disclosed |