Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F13A1 | P00488 | 3/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9838247 | 0.86 | ALDH1A1 (0.39) | F13A1RXFP1MAPTALDH1A1 | |
| SCHEMBL9327608 | 0.82 | MAPT (0.41) | MAPTSCD | |
| SCHEMBL7298216 | 0.80 | ACHE (0.39) | MAPTALDH1A1PTGS2TDP1 | |
| SCHEMBL7302029 | 0.80 | ACHE (0.39) | MAPTALDH1A1PTGS2TDP1 | |
| SCHEMBL9736150 | 0.74 | FFAR4 (0.38) | F13A1 | |
| SCHEMBL10578736 | 0.73 | PDCD4 (0.42) | — | |
| SCHEMBL10576730 | 0.73 | PDCD4 (0.45) | LMNATSHRALDH1A1PTGS1TDP1 | |
| SCHEMBL9766944 | 0.73 | CYP3A4 (0.34) | ALDH1A1PTGS2 | |
| SCHEMBL10431835 | 0.72 | PPARG (0.45) | F13A1MAPTRECQLTBXAS1TDP1 | |
| SCHEMBL2927176 | 0.70 | F13A1 (0.41) | F13A1RXFP1MAPTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5059611-A | Treating psoriasis and modifying calcium homeostatis | ALLERGAN, INC. (US) | 1991-10-22 | — | — | US | disclosed |
| EP-0369812-A2 | Anti-inflammatory 5-hydroxy-2-furanones | ALLERGAN, INC (US) | 1990-05-23 | — | — | EP | disclosed |