Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.32 |
| ▸ | YAP1 | P46937 | 1/20 | 0.32 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.32 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31169261 | 0.74 | SMN1; SMN2 (0.40) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL4866354 | 0.73 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2TEAD1YAP1TEAD4 | |
| SCHEMBL1290037 | 0.73 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL30105977 | 0.72 | CYP2D6 (0.35) | ALDH1A1 | |
| SCHEMBL22833656 | 0.71 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2TEAD1YAP1TEAD4 | |
| SCHEMBL203440 | 0.71 | — | — | |
| SCHEMBL5533465 | 0.70 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2TEAD1YAP1TEAD4 | |
| SCHEMBL11039351 | 0.70 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2TEAD1YAP1TEAD4 | |
| SCHEMBL8038216 | 0.69 | — | — | |
| SCHEMBL7495133 | 0.68 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2TEAD1YAP1TEAD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365541-B1 | PREPARATION OF 5-ACYLAMINO-2,4,6-TRIIODO- OR TRIBROMO-BENZOIC ACID DERIVATIVES | BRACCO S.p.A. (IT) | 1992-08-12 | — | — | EP | disclosed |
| US-5066823-A | Rearrangement reaction, contrast agent for radiology | BRACCO INDUSTRIA CHEMICA S.P.A. (IT) | 1991-11-19 | — | — | US | disclosed |
| EP-0365541-A1 | PREPARATION OF 5-ACYLAMINO-2,4,6-TRIIODO- OR TRIBROMO-BENZOIC ACID DERIVATIVES. | BRACCO IND CHIMICA SPA (IT) | 1990-05-02 | — | — | EP | disclosed |
| WO-1988009328-A1 | PREPARATION OF 5-ACYLAMINO-2,4,6-TRIIODO- OR TRIBROMO-BENZOIC ACID DERIVATIVES | BRACCO INDUSTRIA CHIMICA S.P.A. (IT) | 1988-12-01 | — | — | WO | disclosed |