Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | FABP1 | P07148 | 1/20 | 0.53 |
| ▸ | FABP6 | P51161 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735532 | 0.81 | PARP1 (0.49) | KMT2AALDH1A1KDM4EHTT | |
| SCHEMBL15692575 | 0.80 | KMT2A (0.70) | SMN1; SMN2LMNAKMT2ATSHRMEN1 | |
| SCHEMBL8824257 | 0.80 | L3MBTL1 (0.62) | SMN1; SMN2LMNATSHRALDH1A1KDM4E | |
| SCHEMBL9735095 | 0.80 | PARP1 (0.51) | — | |
| SCHEMBL9734496 | 0.79 | KMT2A (0.53) | SMN1; SMN2LMNAKMT2ATSHRMEN1 | |
| SCHEMBL27663681 | 0.78 | ALDH1A1 (0.70) | LMNAKMT2ATSHRMEN1ALDH1A1 | |
| SCHEMBL9735099 | 0.77 | POLB (0.53) | SMN1; SMN2LMNAKMT2AALDH1A1KDM4E | |
| SCHEMBL8916375 | 0.77 | KMT2A (0.72) | SMN1; SMN2LMNAKMT2ATSHRMEN1 | |
| SCHEMBL2853078 | 0.76 | KMT2A (0.70) | LMNAKMT2ATSHRMEN1ALDH1A1 | |
| SCHEMBL8917314 | 0.76 | KMT2A (0.74) | SMN1; SMN2LMNAKMT2ATSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102882-A | Nootropic agents | NIPPON SHINYAKU CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |