Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GPR183 | P32249 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LSS | P48449 | 1/20 | 0.44 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735095 | 0.89 | PARP1 (0.51) | PARP1 | |
| SCHEMBL8824257 | 0.89 | L3MBTL1 (0.62) | PARP1POLBKDM4EALDH1A1MAPT | |
| SCHEMBL9734496 | 0.89 | KMT2A (0.53) | POLBKDM4EALDH1A1KMT2AEPHX2 | |
| SCHEMBL9734613 | 0.86 | GFER (0.50) | PARP1POLBALDH1A1GPR183KMT2A | |
| SCHEMBL9735099 | 0.86 | POLB (0.53) | POLBKDM4EALDH1A1HTTL3MBTL1 | |
| SCHEMBL9736225 | 0.84 | KDM4E (0.51) | KDM4EALDH1A1MAPTL3MBTL1KMT2A | |
| SCHEMBL9736130 | 0.82 | NAMPT (0.61) | AKR1C3ALDH1A1HTTNPSR1KMT2A | |
| SCHEMBL9735854 | 0.82 | KMT2A (0.58) | PARP1AKR1C3POLBALDH1A1MAPT | |
| SCHEMBL9735195 | 0.82 | ALDH1A1 (0.52) | PARP1POLBALDH1A1HTTFAAH | |
| SCHEMBL9736208 | 0.81 | SMN1; SMN2 (0.62) | KDM4EALDH1A1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102882-A | Nootropic agents | NIPPON SHINYAKU CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |