Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12641440 | 0.85 | LMNA (0.30) | LMNA | |
| SCHEMBL14556006 | 0.83 | MGAM (0.39) | LMNAPTPN1THRB | |
| SCHEMBL16882838 | 0.83 | LMNA (0.44) | LMNAPTPN1TSHR | |
| SCHEMBL28507455 | 0.83 | TSHR (0.38) | LMNAPTPN1THRBTSHR | |
| SCHEMBL15950230 | 0.81 | LMNA (0.33) | LMNATHRBTSHR | |
| SCHEMBL3744813 | 0.80 | — | — | |
| SCHEMBL18043562 | 0.79 | — | — | |
| SCHEMBL5051721 | 0.79 | LMNA (0.41) | LMNAPTPN1TSHR | |
| SCHEMBL9318642 | 0.76 | LMNA (0.33) | LMNA | |
| SCHEMBL12201817 | 0.74 | THRB (0.35) | LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162552-A | PREPARATION OF 4-ACETALS OF BUTENE-1,4-DIAL AND NOVEL ACETALS OF BUTENE-1,4-DIAL | BASF AKTIENGESELLSCHAFT (DE) | 1992-11-10 | — | — | US | disclosed |