Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 2/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | XBP1 | P17861 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736298 | 1.00 | ALDH1A1 (0.48) | ALDH1A1NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9125192 | 0.77 | RAB9A (0.54) | ALDH1A1NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9125199 | 0.77 | RAB9A (0.54) | ALDH1A1NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL4047300 | 0.74 | ALDH1A1 (0.54) | ALDH1A1NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL27417397 | 0.74 | HPGD (0.43) | ALDH1A1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL27692108 | 0.70 | HSD17B10 (0.42) | ALDH1A1NPC1LMNAPAX8PPARG | |
| SCHEMBL27476781 | 0.70 | ALDH1A1 (0.43) | ALDH1A1MAPTSMN1; SMN2LMNAHPGD | |
| SCHEMBL27476782 | 0.70 | ALDH1A1 (0.43) | ALDH1A1MAPTSMN1; SMN2LMNAHPGD | |
| SCHEMBL18979949 | 0.67 | RAB9A (0.67) | ALDH1A1NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL12668379 | 0.66 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNANPSR1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992012137-A1 | NOVEL 3(2H)-PYRIDAZINONES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1992-07-23 | — | — | WO | disclosed |