Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.37 |
| ▸ | GFER | P55789 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9264795 | 0.81 | KDM4E (0.56) | GAAALDH1A1KDM4EMEN1POLB | |
| SCHEMBL9844694 | 0.78 | HRH3 (0.47) | ALDH1A1KDM4EMEN1POLBHPGD | |
| SCHEMBL2019621 | 0.75 | MAOB (0.51) | GAAALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL9387355 | 0.68 | HTR2A (0.41) | ALDH1A1RPS6KA2KDM4EKMT2AHSD17B10 | |
| SCHEMBL9789564 | 0.67 | LTA4H (0.67) | GAAALDH1A1MEN1KMT2AGSTP1 | |
| SCHEMBL11719516 | 0.64 | MEN1 (0.64) | GALR3GAAALDH1A1KDM4EMEN1 | |
| SCHEMBL9515088 | 0.63 | LTA4H (0.60) | GAAALDH1A1MEN1KMT2AGSTP1 | |
| SCHEMBL4402154 | 0.63 | LTA4H (0.60) | GAAKDM4EMEN1KMT2AGSTP1 | |
| SCHEMBL29860094 | 0.63 | LTA4H (0.60) | GAAKDM4EMEN1KMT2AGSTP1 | |
| SCHEMBL1745079 | 0.62 | GRM5 (0.53) | HSD17B10GSTP1HRH3MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992021678-A1 | LIPOXYGENASE INHIBITING PYRROLO [1,2a]INDOLE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-12-10 | — | — | WO | disclosed |