Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6051985 | 0.82 | PKM (0.43) | PKMCHEK1HSD17B10CA12CA1 | |
| SCHEMBL9174441 | 0.81 | PKM (0.42) | PKMCHEK1HSD17B10CA12CA1 | |
| SCHEMBL8992541 | 0.79 | GRIN2D (0.47) | ALDH1A1KDM4EMAPTKMT2ATDP1 | |
| SCHEMBL6052191 | 0.79 | PKM (0.40) | PKMCHEK1HSD17B10CA12CA1 | |
| SCHEMBL284553 | 0.78 | GABRA1 (0.39) | ALDH1A1KDM4EMAPTKMT2AGAA | |
| SCHEMBL29466093 | 0.78 | GABRA1 (0.39) | ALDH1A1KDM4EMAPTKMT2AGAA | |
| SCHEMBL11018140 | 0.78 | USP2 (0.46) | CHEK1HSD17B10SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9173244 | 0.78 | PKM (0.40) | PKMCHEK1HSD17B10CA12CA1 | |
| SCHEMBL2725013 | 0.78 | GAA (0.44) | CA2ALDH1A1KDM4EGAA | |
| SCHEMBL11218056 | 0.78 | GRIN2D (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992021681-A1 | NOVEL CEPHALOSPORINS AND PROCESSES FOR PREPARATION THEREOF | DAE WONG PHARMACEUTICAL CO., LTD. (KR) | 1992-12-10 | — | — | WO | disclosed |