SCHEMBL9736631

SCHEMBL9736631

CCCSc1nc2ccccc2o1.O=C(O)CC(Cc1ccccc1)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CPA1 P15085 2/20 0.51
CPB1 P15086 1/20 0.51
CPA3 P15088 1/20 0.51
CPB2 Q96IY4 1/20 0.51
ALDH1A1 P00352 2/20 0.49
SMN1; SMN2 Q16637 4/20 0.47
HPGD P15428 2/20 0.47
CYP1A2 P05177 2/20 0.47
CYP2C9 P11712 2/20 0.47
CYP2C19 P33261 2/20 0.47
GFER P55789 1/20 0.47
KMT2A Q03164 5/20 0.47
RAB9A P51151 4/20 0.47
MEN1 O00255 4/20 0.47
NPC1 O15118 3/20 0.47
L3MBTL1 Q9Y468 3/20 0.47
TDP1 Q9NUW8 2/20 0.47
ATM Q13315 1/20 0.47
DDAH1 O94760 1/20 0.46
ADRA2C P18825 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9734846 0.93 HPGD (0.59) CPA1CPB1CPA3CPB2ALDH1A1
SCHEMBL8973462 0.81 KMT2A (0.56) ALDH1A1SMN1; SMN2HPGDCYP1A2CYP2C9
Ammonia Solution, Strong SCHEMBL10890190 0.79 KMT2A (0.55) ALDH1A1SMN1; SMN2HPGDCYP1A2CYP2C9
SCHEMBL10894262 0.79 KMT2A (0.55) ALDH1A1SMN1; SMN2HPGDCYP1A2CYP2C9
Ammonia Solution, Strong SCHEMBL10867243 0.79 KMT2A (0.55) ALDH1A1SMN1; SMN2HPGDCYP1A2CYP2C9
Dimethylamine SCHEMBL10893716 0.79 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2HPGDCYP1A2CYP2C9
Dimethylamine SCHEMBL10893710 0.79 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2HPGDCYP1A2CYP2C9
SCHEMBL5020552 0.79 DDAH1 (0.71) ALDH1A1SMN1; SMN2HPGDKMT2ARAB9A
SCHEMBL11017110 0.76 KMT2A (0.54) ALDH1A1SMN1; SMN2HPGDKMT2ARAB9A
SCHEMBL10888610 0.75 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2HPGDCYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5152929-A Corrosion inhibitors for water systems CIBA-GEIGY CORPORATION (US) 1992-10-06 US disclosed