Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736303 | 0.85 | MALT1 (0.36) | MALT1 | |
| SCHEMBL9735577 | 0.78 | NPSR1 (0.33) | MALT1PBRM1NPSR1KDM4EMAPT | |
| SCHEMBL9734747 | 0.78 | NSD2 (0.32) | — | |
| SCHEMBL9735400 | 0.77 | KDM4E (0.35) | NPSR1KDM4E | |
| SCHEMBL9734213 | 0.77 | PBRM1 (0.33) | MALT1PBRM1NPSR1CYP19A1 | |
| SCHEMBL9737951 | 0.72 | PTGER1 (0.34) | MALT1NPSR1KDM4EMAPT | |
| SCHEMBL9737036 | 0.71 | NPSR1 (0.32) | NPSR1KDM4EMAPT | |
| SCHEMBL9736148 | 0.67 | XIAP (0.32) | PBRM1 | |
| SCHEMBL9735702 | 0.65 | PBRM1 (0.31) | PBRM1 | |
| SCHEMBL8539965 | 0.65 | MAPT (0.43) | PBRM1NPSR1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |