Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | CASP4 | P49662 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | CASP9 | P55211 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737951 | 0.85 | PTGER1 (0.34) | MALT1POLBKMT2AKDM4ETSHR | |
| SCHEMBL9147582 | 0.85 | KMT2A (0.40) | NR1H4MALT1CASP6POLBAPEX1 | |
| SCHEMBL8345414 | 0.83 | MALT1 (0.39) | NR1H4MALT1CASP6POLBAPEX1 | |
| SCHEMBL9735762 | 0.83 | ABCC9 (0.42) | MALT1HTTCASP3TSHRSMN1; SMN2 | |
| SCHEMBL9737143 | 0.82 | ALDH1A1 (0.36) | POLBRAB9AKDM4ECASP3ALDH1A1 | |
| SCHEMBL9735458 | 0.82 | NR1H4 (0.39) | NR1H4MALT1CASP6POLBAPEX1 | |
| SCHEMBL9147881 | 0.78 | NR1H4 (0.39) | NR1H4MALT1CASP6POLBAPEX1 | |
| SCHEMBL9737279 | 0.78 | CHRM2 (0.34) | MALT1CASP6POLBKMT2AMEN1 | |
| SCHEMBL9144351 | 0.77 | CASP6 (0.39) | NR1H4MALT1CASP6POLBAPEX1 | |
| SCHEMBL9148890 | 0.77 | MEN1 (0.38) | NR1H4MALT1CASP6POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |