Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
| ▸ | S100A4 | P26447 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735577 | 0.85 | NPSR1 (0.33) | MALT1MAPT | |
| SCHEMBL9736807 | 0.79 | MALT1 (0.36) | MALT1ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL9735589 | 0.78 | CCNE1 (0.35) | MALT1ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL9735811 | 0.78 | MEN1 (0.33) | ALDH1A1NPC1MAPTRAB9ACYP3A4 | |
| SCHEMBL9737094 | 0.74 | MALT1 (0.35) | MALT1ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL9735458 | 0.73 | NR1H4 (0.39) | MALT1ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL9734455 | 0.73 | MALT1 (0.35) | MALT1ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL8539954 | 0.72 | NPC1 (0.44) | MALT1ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL8316461 | 0.71 | L3MBTL1 (0.41) | ALDH1A1AKR1B1NR3C1PGRNR3C2 | |
| SCHEMBL8314877 | 0.71 | MEN1 (0.36) | ALDH1A1MAPTAKR1B1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |