Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | ANPEP | P15144 | 2/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736813 | 0.84 | CA12 (0.39) | ALDH1A1KMT2ALMNAL3MBTL1MEN1 | |
| SCHEMBL9737270 | 0.84 | ALDH1A1 (0.47) | ALDH1A1KMT2ALMNAL3MBTL1MEN1 | |
| SCHEMBL7305676 | 0.83 | KMT2A (0.36) | ALDH1A1KMT2ALMNAL3MBTL1MEN1 | |
| SCHEMBL7302546 | 0.83 | KMT2A (0.36) | ALDH1A1KMT2ALMNAL3MBTL1MEN1 | |
| SCHEMBL7301910 | 0.83 | KMT2A (0.36) | ALDH1A1KMT2ALMNAL3MBTL1MEN1 | |
| SCHEMBL4367951 | 0.82 | MMP2 (0.40) | ALDH1A1KMT2ALMNAMEN1CA12 | |
| SCHEMBL6857780 | 0.80 | MMP2 (0.35) | CA12MMP2ANPEP | |
| SCHEMBL6978918 | 0.80 | FKBP1A (0.44) | ALDH1A1FKBP1A | |
| SCHEMBL6978913 | 0.80 | FKBP1A (0.44) | ALDH1A1FKBP1A | |
| SCHEMBL5416492 | 0.80 | FKBP1A (0.44) | ALDH1A1FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251164-B1 | NEW CHIRAL PHOSPHINOPYRROLIDINE COMPOUNDS AND THEIR USE FOR ASYMETRIC SYNTHESIS OF OPTICALLY ACTIVE COMPOUNDS | Achiwa, Kazuo (JP) | 1992-12-16 | — | — | EP | disclosed |
| US-4879389-A | HYDROGENATION CATALYSTS | ACHIWA KAZUO (JP) | 1989-11-07 | — | — | US | disclosed |
| EP-0251164-A2 | New chiral phosphinopyrrolidine compounds and their use for asymetric synthesis of optically active compounds | Achiwa, Kazuo (JP) | 1988-01-07 | — | — | EP | disclosed |