Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738250 | 0.83 | OPRM1 (0.36) | F10HTR1AHTR1DHTR2CTRPV1 | |
| SCHEMBL9195542 | 0.82 | ABCC9 (0.41) | — | |
| SCHEMBL9735583 | 0.77 | OPRM1 (0.36) | F10OPRM1DRD3DRD2OPRK1 | |
| SCHEMBL8090456 | 0.74 | ABCC9 (0.46) | — | |
| SCHEMBL9734831 | 0.73 | ALOX5 (0.37) | OPRM1TSHRHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL8088453 | 0.73 | F10 (0.33) | F10HTR1AHTR1DHTR2COPRM1 | |
| SCHEMBL9735438 | 0.72 | HTR1A (0.40) | HTR1AHTR1DHTR2COPRM1TSHR | |
| SCHEMBL9735486 | 0.70 | ALOX5 (0.36) | OPRM1TSHRHPGDALDH1A1MAPT | |
| SCHEMBL9735412 | 0.69 | ABCC9 (0.32) | TRPV1DRD2 | |
| SCHEMBL9736615 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415065-B1 | Chroman derivatives | MERCK PATENT GMBH (DE) | 1995-06-28 | — | — | EP | disclosed |
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |
| EP-0415065-A1 | Chroman derivatives | MERCK PATENT GmbH (DE) | 1991-03-06 | — | — | EP | disclosed |