Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 9/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736730 | 0.85 | AVPR1B (0.35) | HTR6ALDH1A1PTGS1PTGS2 | |
| SCHEMBL6860540 | 0.74 | HTR6 (0.50) | HTR6POLBL3MBTL1HDAC3HDAC4 | |
| SCHEMBL3967910 | 0.72 | HTR6 (0.50) | HTR6POLBL3MBTL1HDAC3HDAC4 | |
| SCHEMBL9737717 | 0.72 | HTR6 (0.60) | HTR6POLBL3MBTL1HDAC3HDAC4 | |
| SCHEMBL3555665 | 0.71 | HTR6 (0.63) | HTR6POLBL3MBTL1HDAC3HDAC4 | |
| SCHEMBL9737232 | 0.70 | TUBB4A (0.40) | MEN1KMT2AALDH1A1HTT | |
| SCHEMBL9736220 | 0.69 | KDM4E (0.44) | POLBHDAC6MEN1KMT2AALDH1A1 | |
| SCHEMBL6867966 | 0.69 | HTR6 (0.48) | HTR6POLBL3MBTL1HDAC3HDAC4 | |
| SCHEMBL6860260 | 0.68 | HTR6 (0.59) | HTR6POLBL3MBTL1HDAC3HDAC4 | |
| SCHEMBL3561484 | 0.68 | ACLY (0.65) | HTR6POLBL3MBTL1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079363-A | From an alkoxypyridine and an indole derivative, antitumor and antileukemia agents | SANOFI (FR) | 1992-01-07 | — | — | US | disclosed |