Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9845023 | 0.91 | CA12 (0.34) | CA12CA9RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9845019 | 0.83 | CA12 (0.34) | CA12CA9RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9735212 | 0.82 | CA12 (0.34) | CA12CA9RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9735584 | 0.80 | ALOX5 (0.34) | CA12CA9RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL22997428 | 0.79 | RAB9A (0.42) | CA12CA9RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL29653996 | 0.79 | RAB9A (0.42) | CA12CA9RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL29446214 | 0.79 | RAB9A (0.42) | CA12CA9RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL29446222 | 0.79 | RAB9A (0.42) | CA12CA9RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL29446212 | 0.79 | RAB9A (0.42) | CA12CA9RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL29653912 | 0.79 | RAB9A (0.42) | CA12CA9RAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |