Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9845066 | 0.85 | SMN1; SMN2 (0.31) | SMN1; SMN2 | |
| SCHEMBL9737241 | 0.83 | CA12 (0.36) | CA12CA9ALOX5SMN1; SMN2NPC1 | |
| SCHEMBL9845023 | 0.81 | CA12 (0.34) | CA12CA9ALOX5SMN1; SMN2NPC1 | |
| SCHEMBL9443581 | 0.76 | CA12 (0.38) | CA12CA9ALOX5SMN1; SMN2NPC1 | |
| SCHEMBL9735212 | 0.72 | CA12 (0.34) | CA12CA9ALOX5SMN1; SMN2NPC1 | |
| SCHEMBL9443525 | 0.69 | ALDH1A1 (0.38) | CA12CA9SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9443541 | 0.68 | AKR1B1 (0.32) | KDM4ECHRNB2CHRNA4 | |
| SCHEMBL9443653 | 0.68 | TDP1 (0.35) | SMN1; SMN2NPC1RAB9AKDM4EMAPT | |
| SCHEMBL9874273 | 0.68 | ABCC9 (0.53) | KDM4ELMNA | |
| SCHEMBL7963353 | 0.68 | ALOX5 (0.38) | CA12CA9ALOX5SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415065-A1 | Chroman derivatives | MERCK PATENT GmbH (DE) | 1991-03-06 | — | — | EP | disclosed |