Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.46 |
| ▸ | RARB | P10826 | 2/20 | 0.46 |
| ▸ | RARG | P13631 | 2/20 | 0.46 |
| ▸ | RARA | P10276 | 1/20 | 0.46 |
| ▸ | ESRRA | P11474 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | SNCA | P37840 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7594781 | 0.84 | LMNA (0.46) | CA1CA2SNCACYP3A4ALDH1A1 | |
| SCHEMBL5364276 | 0.82 | CA12 (0.68) | HSP90AA1HSP90AB1NR1H4RARBRARG | |
| SCHEMBL2972468 | 0.82 | CA12 (0.62) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9737503 | 0.81 | CA1 (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7940256 | 0.79 | HSP90AA1 (0.52) | HSP90AA1HSP90AB1NR1H4RARBRARG | |
| SCHEMBL8839323 | 0.79 | KMT2A (0.49) | SNCACYP3A4ALDH1A1LMNAHSD17B10 | |
| SCHEMBL680754 | 0.78 | HSD17B2 (0.68) | HSP90AA1HSP90AB1CA12CA1CA2 | |
| SCHEMBL9125713 | 0.78 | SNCA (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11274983 | 0.78 | ALDH1A1 (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9419972 | 0.77 | SNCA (0.54) | CA1CA2SNCACYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173289-A | Skin disorders, antiinflammatory agents | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (C.I.R.D.) (FR) | 1992-12-22 | — | — | US | disclosed |
| US-4925658-A | TREATMENT OF DERMATOLOGIC, RHEUMATIC, RESPIRATORY, OPHTHALMOLOGIC DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (CIRD) (FR) | 1990-05-15 | — | — | US | disclosed |