Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | EGFR | P00533 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736861 | 0.88 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAEGFRALDH1A1HPGD | |
| SCHEMBL13701715 | 0.84 | SMN1; SMN2 (0.57) | SMN1; SMN2LMNAEGFRALDH1A1HPGD | |
| SCHEMBL27515551 | 0.78 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAEGFRALDH1A1HPGD | |
| SCHEMBL28360960 | 0.77 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAEGFRALDH1A1HPGD | |
| SCHEMBL24003686 | 0.76 | P2RX7 (0.64) | SMN1; SMN2LMNAEGFRALDH1A1HPGD | |
| SCHEMBL1467988 | 0.76 | SMN1; SMN2 (0.61) | SMN1; SMN2LMNAEGFRALDH1A1HPGD | |
| SCHEMBL13702282 | 0.75 | SMN1; SMN2 (0.59) | SMN1; SMN2LMNAEGFRALDH1A1HPGD | |
| SCHEMBL6992077 | 0.74 | SMN1; SMN2 (0.63) | SMN1; SMN2LMNAEGFRALDH1A1HPGD | |
| SCHEMBL27476499 | 0.74 | SMN1; SMN2 (0.63) | SMN1; SMN2LMNAEGFRALDH1A1HPGD | |
| SCHEMBL13116725 | 0.73 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNAEGFRALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079363-A | From an alkoxypyridine and an indole derivative, antitumor and antileukemia agents | SANOFI (FR) | 1992-01-07 | — | — | US | disclosed |