Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9656488 | 0.90 | LMNA (0.53) | LMNATP53MAPTALDH1A1THRB | |
| SCHEMBL9319006 | 0.80 | LMNA (0.47) | LMNATP53MAPTALDH1A1KDM4E | |
| SCHEMBL6504657 | 0.79 | KDM4E (0.39) | LMNATP53MAPTGAAKDM4E | |
| SCHEMBL6493729 | 0.78 | LMNA (0.38) | LMNAMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL6504047 | 0.77 | THRB (0.40) | LMNATP53MAPTALDH1A1KDM4E | |
| SCHEMBL9318146 | 0.75 | PTGER4 (0.40) | KDM4EMEN1KMT2A | |
| SCHEMBL25952548 | 0.75 | PTGER4 (0.37) | TP53MAPTALDH1A1GAATHRB | |
| SCHEMBL30149296 | 0.74 | GLP1R (0.41) | TP53MAPTALDH1A1GAAKDM4E | |
| SCHEMBL25543735 | 0.74 | GLP1R (0.41) | TP53MAPTALDH1A1GAAKDM4E | |
| SCHEMBL6491247 | 0.73 | ALOX5AP (0.38) | ALDH1A1HPGDMEN1KMT2AENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992020679-A1 | BENZOFURAN DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1992-11-26 | — | — | WO | disclosed |