Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770003 | 1.00 | PTPN1 (0.37) | PTPN1PTPRCALDH1A1HCAR2KMT2A | |
| SCHEMBL9736749 | 0.81 | CA1 (0.35) | PTPN1PTPRCKMT2AMAPK1TSHR | |
| SCHEMBL9735971 | 0.81 | CA1 (0.35) | PTPN1PTPRCKMT2AMAPK1TSHR | |
| SCHEMBL9737400 | 0.77 | CA1 (0.38) | PTPN1KMT2AMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL9737641 | 0.77 | CA1 (0.38) | PTPN1KMT2AMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL10769664 | 0.71 | HTR2A (0.42) | ALDH1A1MAPTRAB9A | |
| SCHEMBL9065651 | 0.69 | ALDH1A1 (0.57) | ALDH1A1HCAR2KMT2AMAPK1L3MBTL1 | |
| SCHEMBL454115 | 0.68 | ALDH1A1 (0.63) | ALDH1A1HCAR2KMT2AMAPK1L3MBTL1 | |
| SCHEMBL6686180 | 0.66 | ALDH1A1 (0.59) | ALDH1A1KMT2AMAPK1SLC6A2SLC6A3 | |
| SCHEMBL29327549 | 0.66 | ALDH1A1 (0.52) | ALDH1A1HCAR2KMT2AMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118820-A | Carbohydrate is chemical intermediate for nucleoside | ELI LILLY AND COMPANY (US) | 1992-06-02 | — | — | US | disclosed |
| US-5015743-A | 2-Deoxy-2,2-difluororibose | ELI LILLY AND COMPANY (US) | 1991-05-14 | — | — | US | disclosed |
| US-4808614-A | Difluoro antivirals and intermediate therefor | ELI LILLY AND COMPANY (US) | 1989-02-28 | — | — | US | disclosed |
| EP-0122707-B1 | IMPROVEMENTS IN OR RELATING TO NOVEL DIFLUORO ANTIVIRAL AGENTS | ELI LILLY AND COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |
| US-4692434-A | NUCLEOSIDES | ELI LILLY AND COMPANY (US) | 1987-09-08 | — | — | US | disclosed |
| EP-0211354-A2 | Nucleosides and their use as antineoplastic agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1987-02-25 | — | — | EP | disclosed |
| US-4526988-A | Hydrolyzing alkyl 3-dioxolanyl-2,2-difluoro-3-hydroxy propionate | ELI LILLY AND COMPANY (US) | 1985-07-02 | — | — | US | disclosed |
| EP-0122707-A1 | Improvements in or relating to novel difluoro antiviral agents | ELI LILLY AND COMPANY (US) | 1984-10-24 | — | — | EP | disclosed |