Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735971 | 1.00 | CA1 (0.35) | CA1PTPN1CA2CA7CA9 | |
| SCHEMBL9737641 | 0.88 | CA1 (0.38) | CA1PTPN1CA2CA7CA9 | |
| SCHEMBL9737400 | 0.88 | CA1 (0.38) | CA1PTPN1CA2CA7CA9 | |
| SCHEMBL9770003 | 0.81 | PTPN1 (0.37) | PTPN1PTPRCTSHRKMT2AMEN1 | |
| SCHEMBL9737639 | 0.81 | PTPN1 (0.37) | PTPN1PTPRCTSHRKMT2AMEN1 | |
| SCHEMBL8992078 | 0.69 | SLC1A1 (0.41) | CA1CA2CA7CA9SLC1A3 | |
| SCHEMBL4412607 | 0.69 | CA1 (0.43) | CA1CA2CA7CA9TSHR | |
| SCHEMBL620071 | 0.68 | CA1 (0.53) | CA1CA2CA7CA9TSHR | |
| SCHEMBL4411606 | 0.66 | CA1 (0.41) | CA1CA2CA7CA9TSHR | |
| SCHEMBL4409725 | 0.66 | CA1 (0.41) | CA1CA2CA7CA9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118820-A | Carbohydrate is chemical intermediate for nucleoside | ELI LILLY AND COMPANY (US) | 1992-06-02 | — | — | US | disclosed |
| US-5015743-A | 2-Deoxy-2,2-difluororibose | ELI LILLY AND COMPANY (US) | 1991-05-14 | — | — | US | disclosed |
| US-4808614-A | Difluoro antivirals and intermediate therefor | ELI LILLY AND COMPANY (US) | 1989-02-28 | — | — | US | disclosed |
| EP-0122707-B1 | IMPROVEMENTS IN OR RELATING TO NOVEL DIFLUORO ANTIVIRAL AGENTS | ELI LILLY AND COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |
| US-4692434-A | NUCLEOSIDES | ELI LILLY AND COMPANY (US) | 1987-09-08 | — | — | US | disclosed |
| EP-0211354-A2 | Nucleosides and their use as antineoplastic agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1987-02-25 | — | — | EP | disclosed |
| US-4526988-A | Hydrolyzing alkyl 3-dioxolanyl-2,2-difluoro-3-hydroxy propionate | ELI LILLY AND COMPANY (US) | 1985-07-02 | — | — | US | disclosed |
| EP-0122707-A1 | Improvements in or relating to novel difluoro antiviral agents | ELI LILLY AND COMPANY (US) | 1984-10-24 | — | — | EP | disclosed |