Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5322133 | 0.73 | NPSR1 (0.51) | SMN1; SMN2NPSR1MAPTALDH1A1RAB9A | |
| SCHEMBL5771929 | 0.71 | NR4A2 (0.42) | SMN1; SMN2MAPTALDH1A1RAB9AHTT | |
| SCHEMBL13890096 | 0.67 | SMN1; SMN2 (0.45) | SMN1; SMN2CYP3A4CYP1A2 | |
| SCHEMBL9742210 | 0.66 | KDM4E (0.32) | MAPTALDH1A1RAB9APTGESCYP3A4 | |
| SCHEMBL15330789 | 0.66 | NPSR1 (0.51) | SMN1; SMN2NPSR1MAPTALDH1A1RAB9A | |
| SCHEMBL4804422 | 0.64 | SMN1; SMN2 (0.68) | SMN1; SMN2NPSR1MAPTALDH1A1RAB9A | |
| SCHEMBL7104339 | 0.63 | DYRK1A (0.37) | SMN1; SMN2MAPTALDH1A1KDM4EGAA | |
| SCHEMBL11262568 | 0.62 | KDM4E (0.32) | NPSR1MAPTALDH1A1KDM4E | |
| SCHEMBL13969630 | 0.61 | KDM4E (0.35) | MAPTALDH1A1KDM4E | |
| SCHEMBL1665868 | 0.61 | LMNA (0.38) | SMN1; SMN2MAPTALDH1A1PTGESCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006979-A1 | NEW DIAZINES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1992-04-30 | — | — | WO | disclosed |
| WO-1991017164-A1 | NOVEL PYRIDAZINES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1991-11-14 | — | — | WO | disclosed |