Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8079176 | 0.78 | LRRK2 (0.32) | GAAALDH1A1HPGD | |
| SCHEMBL14193495 | 0.72 | — | — | |
| SCHEMBL7902863 | 0.68 | KDM4C (0.53) | DYRK1APDE4DL3MBTL1ARGAA | |
| SCHEMBL11262568 | 0.68 | KDM4E (0.32) | MAPTHSD17B10ALDH1A1KDM4EHPGD | |
| SCHEMBL19212313 | 0.67 | ALDH1A1 (0.35) | ALDH1A1HPGD | |
| SCHEMBL17979462 | 0.67 | — | — | |
| SCHEMBL9852813 | 0.65 | NPSR1 (0.34) | GAAPKMHSD17B10ALDH1A1KDM4E | |
| SCHEMBL20310207 | 0.65 | LMNA (0.41) | DYRK1AL3MBTL1LMNACYP2C19MAPT | |
| SCHEMBL11112731 | 0.65 | KDM4E (0.33) | MAPK1MAPTHSD17B10ALDH1A1KDM4E | |
| SCHEMBL8090576 | 0.65 | KDM4C (0.45) | L3MBTL1ARGAALMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091940-B1 | METHOD FOR PREPARING 1-ALKYL-PYRAZOL-5-CARBOXYLIC ACID ESTERS | BAYER AG (DE) | 2003-09-10 | — | — | EP | disclosed |
| EP-0854142-B1 | Process for the preparation of 1-alkylpyrazole-5-carboxylic esters | BAYER AG (DE) | 2002-09-18 | — | — | EP | disclosed |
| EP-1091940-A1 | METHOD FOR PREPARING 1-ALKYL-PYRAZOL-5-CARBOXYLIC ACID ESTERS | Bayer Aktiengesellschaft (DE) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001673-A2 | METHOD FOR PREPARING 1-ALKYL-PYRAZOL-5-CARBOXYLIC ACID ESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-01-13 | — | — | WO | disclosed |
| EP-0854142-A1 | Process for the preparation of 1-alkylpyrazole-5-carboxylic esters | BAYER AG (DE) | 1998-07-22 | — | — | EP | disclosed |