Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL568818 | 0.75 | TSHR (0.47) | TSHRMAPTKDM4EGAASMN1; SMN2 | |
| SCHEMBL1713222 | 0.72 | TSHR (0.57) | TSHRMAPTKDM4EGAASMN1; SMN2 | |
| SCHEMBL11072823 | 0.71 | TSHR (0.55) | TSHRMAPTKDM4EGAASMN1; SMN2 | |
| SCHEMBL158497 | 0.71 | TSHR (0.55) | TSHRMAPTKDM4EGAASMN1; SMN2 | |
| SCHEMBL28537408 | 0.70 | TSHR (0.50) | TSHRMAPTKDM4EGAASMN1; SMN2 | |
| SCHEMBL18092279 | 0.70 | MAPT (0.42) | TSHRMAPTKDM4EGAASMN1; SMN2 | |
| SCHEMBL9736657 | 0.70 | TSHR (0.42) | TSHRMAPTKDM4EGAASMN1; SMN2 | |
| SCHEMBL12994041 | 0.69 | TSHR (0.53) | TSHRMAPTKDM4EGAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27776511 | 0.69 | TSHR (0.53) | TSHRMAPTKDM4EGAASMN1; SMN2 | |
| SCHEMBL7447957 | 0.69 | MAPT (0.45) | TSHRMAPTKDM4EGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089621-A | Intermediates for cephalosporins or quinolone derivative antibiotics | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1992-02-18 | — | — | US | disclosed |
| EP-0424852-A1 | Diazabicycloamine compounds and a process for their preparation | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1991-05-02 | — | — | EP | disclosed |