Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PCTP | Q9UKL6 | 1/20 | 0.39 |
| ▸ | STARD10 | Q9Y365 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738056 | 0.87 | LMNA (0.45) | LMNAKMT2AMAPTPCTPSTARD10 | |
| SCHEMBL9739942 | 0.81 | LMNA (0.39) | LMNAKMT2AMAPTPCTPSTARD10 | |
| SCHEMBL9737842 | 0.76 | LMNA (0.36) | LMNAKMT2AMAPTPCTPSTARD10 | |
| SCHEMBL10670733 | 0.73 | POLB (0.50) | KMT2AMAPTKDM4EHTTL3MBTL1 | |
| SCHEMBL11741152 | 0.71 | FSCN1 (0.53) | KMT2AMAPTHTTL3MBTL1MEN1 | |
| SCHEMBL9738164 | 0.70 | KMT2A (0.40) | LMNAKMT2AMAPTCYP1A2CYP2C19 | |
| SCHEMBL11800728 | 0.67 | SMN1; SMN2 (0.42) | LMNAKMT2AMAPTKDM4EHTT | |
| SCHEMBL9511939 | 0.64 | NPSR1 (0.44) | KMT2AKDM4EHTTMEN1NPC1 | |
| SCHEMBL15503848 | 0.63 | LMNA (1.00) | LMNAKMT2AMAPTPCTPSTARD10 | |
| SCHEMBL10642298 | 0.63 | FSCN1 (0.55) | LMNAKMT2AMAPTL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5159078-A | Herbicides, plant growth regulator | CIBA-GEIGY CORPORATION (US) | 1992-10-27 | — | — | US | disclosed |
| US-4966622-A | HERBICIDES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1990-10-30 | — | — | US | disclosed |
| EP-0337943-A2 | N-Phenyl-N-pyrimidin-2-yl-ureas with herbicidal and plant-growth regulating activity | CIBA-GEIGY AG (CH) | 1989-10-18 | — | — | EP | disclosed |