SCHEMBL9737842

SCHEMBL9737842

Cc1cc(C(F)(F)Cl)nc(N(C(N)=O)c2cc(Cl)ccc2Cl)n1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.36
PCTP Q9UKL6 1/20 0.34
STARD10 Q9Y365 1/20 0.34
KMT2A Q03164 3/20 0.33
PDK1 Q15118 2/20 0.33
PDK2 Q15119 2/20 0.33
PDK3 Q15120 2/20 0.33
PDK4 Q16654 2/20 0.33
MAPT P10636 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
KDM4E B2RXH2 2/20 0.33
CD38 P28907 2/20 0.32
HTT P42858 2/20 0.32
CYP1A2 P05177 2/20 0.32
CYP2C19 P33261 2/20 0.32
GAA P10253 1/20 0.32
CYP2C9 P11712 1/20 0.32
TSHR P16473 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ALOX5 P09917 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9737938 0.93 HSP90AA1 (0.38) LMNAPCTPSTARD10KMT2APDK1
SCHEMBL9738056 0.88 LMNA (0.45) LMNAPCTPSTARD10KMT2AMAPT
SCHEMBL9739942 0.84 LMNA (0.39) LMNAPCTPSTARD10KMT2AMAPT
SCHEMBL9737826 0.80 IGF1R (0.44) MAPTHTTGAATSHRSMN1; SMN2
SCHEMBL9739910 0.79 PDE4B (0.35) KMT2AL3MBTL1HTTCYP2C19GAA
SCHEMBL9738659 0.78 HPGD (0.38) LMNAKMT2AMAPTL3MBTL1HTT
SCHEMBL9738307 0.76 LMNA (0.37) LMNAPCTPSTARD10KMT2AMAPT
SCHEMBL9737818 0.76 LMNA (0.46) LMNAPCTPSTARD10KMT2AMAPT
SCHEMBL9738164 0.75 KMT2A (0.40) LMNAKMT2AMAPTL3MBTL1CYP1A2
SCHEMBL9737076 0.74 MAPK14 (0.43) LMNAKMT2AMAPTL3MBTL1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5159078-A Herbicides, plant growth regulator CIBA-GEIGY CORPORATION (US) 1992-10-27 US disclosed
US-4966622-A HERBICIDES, PLANT GROWTH REGULATORS CIBA-GEIGY CORPORATION (US) 1990-10-30 US disclosed